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Transcranial photobiomodulation (tPBM) uses non-invasive near-infrared light (photo) stimulation of different locations on the brain at targeted frequencies (modulation). This process initiates metabolic processes (bio) within brain cells. Photobiomodulation is based on the principle that certain wavelengths of light, particularly in the red to near-infrared spectrum, have the ability to penetrate the skin and skull to reach the brain. When these specific wavelengths are absorbed by the body's cells, they can influence cellular function and metabolism.

Several studies have found that tPBM can enhance brain cell oxygenation and improve cerebral blood flow, metabolic activity, neurogenesis, and neuroprotection by antioxidant and anti-inflammatory pathway activation. tPBM can also help people shift into a desired state (for example focus or deep calm) quickly, with the positive effects lasting up to six hours.

Scientific References

Transcranial infrared laser stimulation produces beneficial cognitive and emotional effects in humans

https://www.sciencedirect.com/science/article/abs/pii/S0306452212011268?via%3Dihub


Improving executive function using transcranial infrared laser stimulation

https://bpspsychub.onlinelibrary.wiley.com/doi/10.1111/jnp.12074


Photobiomodulation for the aging brain

https://www.sciencedirect.com/science/article/pii/S1568163721001628?via%3Dihub


Photobiomodulation improves the frontal cognitive function of older adults

https://onlinelibrary.wiley.com/doi/10.1002/gps.5039


Augmentation of cognitive brain functions with transcranial lasers

https://www.frontiersin.org/articles/10.3389/fnsys.2014.00036/full


Transcranial photobiomodulation with 1064-nm laser modulates brain electroencephalogram rhythms

https://doi.org/10.1117/1.NPh.6.2.025013

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